Executive Director, Medical Affairs - Eosinophilic Esophagitis (EoE)

About Apogee Therapeutics

Founded in 2022, Apogee Therapeutics, Inc. (Ticker: APGE) is a well-funded, Nasdaq listed company that offers the opportunity to work in a fast-paced, highly dynamic environment. At Apogee, you can actively contribute to shaping the company culture, take on various roles and responsibilities, and grow professionally.

Apogee Therapeutics is a clinical-stage biotechnology company advancing novel biologics with potential for differentiated efficacy and dosing in the largest I&I markets, Apogee’s antibody programs are designed to overcome limitations of existing therapies by targeting well-established mechanisms of action and incorporating advanced antibody engineering to optimize half-life and other properties. Zumilokibart (APG777), the company’s most advanced program, is being initially developed for the treatment of atopic dermatitis (AD), which is the largest and one of the least penetrated I&I markets, as well as asthma. With four validated targets in its portfolio, Apogee is seeking to achieve best-in-class efficacy and dosing through monotherapies and combinations of its novel antibodies. Based on a broad pipeline and depth of leadership and expertise, the company believes it can deliver value and meaningful benefit to patients underserved by today’s standard of care.

We are a fast-paced company committed to building an exceptional culture, founded on our C.O.R.E. values: Caring, Original, Resilient and Egoless and a commitment to refusing to stop at “good enough”.

If this sounds like you, keep reading!

Role Summary

We are seeking a strategic, highly experienced Executive Director, Medical Affairs with deep expertise in eosinophilic esophagitis (EoE). This individual will lead the development and execution of Apogee’s global Medical Affairs strategy for EoE, including the development of a clinical site engagement plan, KOL engagement plan, congress presence, advisory board needs, and subject matter expertise on publications and medical communications. This role also includes working closely with many cross-functional stakeholders, including but not limited to, clinical development, clinical operations, biometrics, research and translational medicine, regulatory affairs, business development and strategy, and commercial.

Key Responsibilities

• Develop and execute global Medical Affairs strategy for EoE
• Serve as a senior, strategic, thought partner across multiple teams and forums within Apogee
• Establish global KOL relationships and build scientific leadership in the field
• Support clinical development, site identification, and evidence generation
• Collaborate cross-functionally across multiple teams
• Ensure compliance with all regulatory standards

Ideal Candidate

• Advanced professional degree (PharmD, PhD, MD/DO)
• 10+ years in a progressive biotech or pharmaceutical company with significant experience leading Medical Affairs strategy
• Strong expertise in EoE required
• Additional experience in other inflammation and immunology disease states preferred
• Proven track record of success in Medical Affairs
• Excellent communication and strategic thinking
• Successfully exhibit Apogee’s C.O.R.E. values: Caring, Original, Resilient and Egoless
• Position requires up to 40% travel including mandatory in-person attendance at All Hands meetings typically held twice per year. Additional travel may be required to attend key team meetings and medical or industry conferences, both in the US and Europe

The anticipated salary range for candidates for this role will be $305,000 - $340,000 per year. The final salary offered will depend on several factors, which may include, but is not limited to, relevant years of experience, educational background, and geography.

What We Offer

• A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless
• Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly
• Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
• We provide competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave
• Commitment to growing you professionally and providing access to resources to further your development
• Apogee offers regular all team, in-person meetings to build relationships and problem solve

E-Verify Participation: As part of the I9 verification of authorization to work in the US, Apogee participates in E-Verify. To learn more about E-Verify please review this poster. Apogee Therapeutics is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. To review our privacy policy, click here It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.